Journal article
Poor Long-Term Survival in Patients With Moderate Aortic Stenosis
G Strange, S Stewart, D Celermajer, D Prior, GM Scalia, T Marwick, M Ilton, M Joseph, J Codde, D Playford
Journal of the American College of Cardiology | ELSEVIER SCIENCE INC | Published : 2019
Abstract
Background: Historical data suggesting poor survival in patients with aortic stenosis (AS) who do not undergo treatment are largely confined to patients with severe AS. Objectives: This study sought to determine the prognostic impact of all levels of native valvular AS. Methods: Severity of AS was characterized by convention and by statistical distribution in 122,809 male patients (mean age 61 ± 17 years) and 118,494 female patients (mean age 62 ± 19 years), with measured aortic valve (AV) mean gradient, peak velocity, and/or area. The relationship between AS severity and survival was then examined during median 1,208 days (interquartile range: 598 to 2,177 days) of follow-up. Patients with ..
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Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
The National Echocardiography Database of Australia was originally established with funding support from Actelion, Bayer, and GlaxoSmithKline, and is supported by National Health and Medical Research Council of Australia grant 1055214. Dr. Strange has served on the Scientific Advisory Board for Edwards Lifesciences Australia. Dr. Prior has received speaker fees from Actelion and Novartis. Dr. Marwick has received research grant support for the SUCCOUR study from GE Medical. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose. Deepak L. Bhatt, MD, MPH, served as Guest Editor-in-Chief for this paper.